Scientific Challenges and Implementation Barriers to Translation of Pharmacogenomics in Clinical Practice
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چکیده
منابع مشابه
Scientific Challenges and Implementation Barriers to Translation of Pharmacogenomics in Clinical Practice
The mapping of the human genome and subsequent advancements in genetic technology had provided clinicians and scientists an understanding of the genetic basis of altered drug pharmacokinetics and pharmacodynamics, as well as some examples of applying genomic data in clinical practice. This has raised the public expectation that predicting patients' responses to drug therapy is now possible in e...
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15 صفحه اولPharmacogenomics in Clinical Practice
The Promise of Pharmacogenomics As genomic medicine advances, there is hope that genetic biomarkers will encourage movement away from empirical and population-based treatment approaches to those that are stratified according to better patient outcomes, thus ending a “trial-and-error” approach to therapy.4,6–8 It is estimated that only 50% of patients respond positively to their medications.5,9 ...
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ژورنال
عنوان ژورنال: ISRN Pharmacology
سال: 2013
ISSN: 2090-5173
DOI: 10.1155/2013/641089